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Psychopharmacology and Psychiatry Updates


May 16, 2019

Today’s question is: What if You Can’t Use An SSRI in GAD?

Here is a summary of this episode:

  • The first-line alternatives to SSRIs in GAD are SNRIs, buspirone, hydroxyzine, pregabalin, and bupropion.
  • Benzodiazepines are not recommended first-line agents for GAD due to their prominent side effect profile.
  • Antipsychotics are not recommended as augmenting agents in GAD due to their high risk of metabolic side effects, negative effects on insulin resistance.