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Psychopharmacology and Psychiatry Updates

Dec 28, 2018

Here is a summary of this episode:

  • In patients with liver impairment, it is better to use drugs that are metabolized by phase II enzymes or drugs that are not metabolized by the liver at all.
  • Patients with severe renal impairment may also have liver impairment. Use ⅔ of the recommended dose.
  • Benzodiazepines and Z-drugs are contraindicated in CO2 retainers and those with severe sleep apnea. Opiates are better than benzodiazepines in patients with terminal breathlessness.