Oct 30, 2018
Today’s question is: How to manage an agitated patient?
Here is a summary of this episode:
- Antipsychotics are the mainstay of treatment; addressing
psychotic agitation as well as treating delirium. Haloperidol is
best combined with a benzodiazepine, showing both high efficacy and
low side effect profile.
- There are currently no FDA-approved oral regimens for
agitation. However, there are orally disintegrating formulations of
olanzapine, aripiprazole and risperidone. Asenapine is available in
a sublingual formulation which requires more patient
- Benzodiazepines have anxiolytic and sedating effects but can
produce behavioral disinhibition and cognitive impairment in
patients with dementia.