Do SSRIs Increase Bleeding Risk?

Feb 6, 2019

Today’s question is: Do SSRIs increase the risk of bleeding?

Here is a summary of this episode:

• Prescribe SSRIs with caution in patients with a defect in platelet number or function and those with H.pylori infection.
• Concomitant SSRI and NSAID use is only of concern in patients taking daily and/or high doses.
• Avoid prescribing fluvoxamine with warfarin. There are no other warnings regarding the use of SSRIs and anticoagulants.
• It is generally not recommended to stop an SSRI before delivery and the absolute risk of postpartum bleeding is insignificant except in patients with a bleeding diathesis.

 

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